APS Annual Meeting at Experimental Biology



Functional CNS Circuits in Feeding and Metabolism

Symposium — Sunday, April 3, 2022 — 1:30 PM - 3:00 PM — Convention Center, Room 204A
Neural Control and Autonomic Regulation Section — Chair: Kevin Williams

The brain continuously receives nutrient, hormonal and neural-related input regarding both long-term energy stores and short-term energy availability and transduces this input into response that control energy intake and energy expenditure to maintain energy homeostasis. With advances in neuroscience technologies, including chemogenetics and optogenetics approaches, in vivo fiber photometry and viral track tracing, we are beginning to decode the functional central circuit responsible for the control of feeding. These investigations are giving us new insights into the mechanisms and timing whereby specific neuronal populations receive and integrate input from various different sources to mediate select feeding, metabolic and/or behavioral responses. This research has the potential to identify novel therapeutics for the treatment of obesity and associated metabolic diseases.

Speakers

  • Introduction
    Kevin Williams — Medical Center at Dallas, University of Texas Southwestern

  • Macronutrient Regulation of Hypothalamic Neurons
    J. Nicholas Betley — Biology, University of Pennsylvania

  • Role of the Gut-Brain Axis in the Regulation of Energy Balance
    Darleen Sandoval — Pediatrics, University of Colorado Anschutz Medical Campus

  • Coupling of Thermoregulation and Energy Homeostasis
    Gregory Morton — Medicine at South Lake Union, University of Washington

  • Close
    Kevin Williams — Medical Center at Dallas, University of Texas Southwestern




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