APS Annual Meeting at Experimental Biology

Cerebral and Cardiovascular Dysfunction After a Complicated Pregnancy

Featured Topic — Sunday, April 3, 2022 — 1:30 PM - 3:00 PM — Convention Center, Room 203A
Cardiovascular Section — Chair: Jessica Bradshaw — Co-Chair: Donna Santillan

 Rates of adverse pregnancies have been increasing over the last decades, and women with a history of complicated pregnancies are at increased risk of cardiovascular disease and stroke postpartum. Strikingly, nearly 70% of maternal morbidity and mortality associated with pregnancy complications occurs in the postpartum period, with a leading cause of death being cardiovascular disease. However, the majority of preclinical and clinical studies have focused on maternal morbidity occurring during pregnancy with little focus on maternal health during the postpartum period. Furthermore, an adverse perinatal environment has been associated with increased risk of cardiovascular diseases in offspring later in life. Currently, there is a need to elucidate the underlying mechanisms contributing to maternal and offspring cerebral and cardiovascular dysfunction occurring after a complicated pregnancy in order to identify novel risk assessments, prevention measures, and targeted treatments. This session will highlight basic and translational research that investigate the impact of adverse pregnancies on cerebral and cardiovascular dysfunction in the period following parturition. 


  • Vascular mechanisms contributing to preeclampsia-associated maternal cardiovascular risk 

    Sandra Davidge — Physiology, University of Alberta

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