APS Annual Meeting at Experimental Biology

The Dynamics of Aerodigestion: Chewing, Swallow and Breathing

Symposium — Tuesday, April 5, 2022 — 3:30 PM - 5:00 PM — Convention Center, Room 204C
Respiration Section — Chair: Teresa Pitts — Co-Chair: Rebecca German

Aerodigestion requires the coordination and integration of multiple behaviors in order to move food/liquid from the mouth to the esophagus.  Appropriate responses are dependent on oral, pharyngeal, laryngeal afferent stimulation, second order neurons filtering and integrating the afferent signal, and appropriate efferent and muscular production of behaviors.  Disease or injury can affect this pathway at any point, resulting in impaired reflex behaviors and an increased risk for aspiration and respiratory problems. This symposium will address the regulation of oral function, including chewing and the oral phase of swallow; swallow pathophysiology and use of clinical techniques; respiratory networks necessary for swallow/breathing coordination; and novel brainstem networks in the swallow pattern generator. We will discuss the uses of a variety of techniques from awake behaving large animals to anesthetized reduced preparations, to give an overview of the modern study of swallow from leaders in the field.     


  • Introduction
    Teresa Pitts — Department of Neurological Surgery, University of Louisville
    3:30 PM - 3:35 PM

  • Role of Jaw and Tongue During Drinking, Chewing and Swallowing
    Callum Ross — Organismal Biology and Anatomy, University of Chicago
    3:35 PM - 3:55 PM

  • Pathophysiology of Dysphagia: Using Technology to Translate to Human Medicine
    Teresa Lever — Otolaryngology, University of Missouri
    3:55 PM - 4:15 PM

  • Rostral Brainstem’s Pivotal Role in Swallow-Breathing Coordination
    Mathias Dutschmann — Florey Institute of Neuroscience and Mental Health, University of Melbourne
    4:15 PM - 4:35 PM

  • Optogenetic Tools to Define New Areas of the Swallow Pattern Generator
    Alyssa Huff — Center for Integrative Brain Research, Seattle Children's Research Institute
    4:35 PM - 4:55 PM

  • Closing Remarks
    Rebecca German — Anatomy and Neurobiology, Northeast Ohio Medical University
    4:55 PM - 5:00 PM

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