APS Annual Meeting at Experimental Biology



Highs and Lows in Autonomic Regulation of Blood Pressure: The Role of Biological Sex and Race

Featured Topic — Sunday, April 3, 2022 — 1:30 PM - 3:00 PM — Convention Center, Room 201B
Environmental and Exercise Physiology Section — Chair: Nisha Charkoudian — Co-Chair: Megan Wenner

It has been known for several decades that autonomic regulation of arterial blood pressure interacts closely with the hormonal regulation of fluid volume and sodium homeostasis. More recently, it has become clear that the influences of sodium on cardiovascular function extend to other areas of cardiovascular control as well. For the most part, historical research studies which have led to these conclusions have been conducted in white men. Where women and BIPOC individuals have been included, it is often the case that sex and race analyses were not conducted, often due to a lack of statistical power (i.e., not enough women or people of color). In the present Featured Topic, our goals are to encourage discussion of differences between races and/or differences between males and females regarding autonomic, vascular and/or renal mechanisms contributing to the regulation of blood pressure and blood flow. The timeliness of this Featured Topic is highlighted by great enthusiasm from the field related to a recent Journal of Applied Physiology Point: Counterpoint series led by one of our co-chairs (Dr. Wenner, PMID: 32702264) on controlling for menstrual cycle phase in vascular control studies. Additionally, our other co-chair and featured speaker (Drs. Charkoudian and Robinson) served as guest editors on a recent call for papers on racial differences in cardiovascular and cerebrovascular physiology for the American Journal of Physiology; Heart and Circulatory Physiology (PMID: 32618515) that also generated a lot of interest from the field. Further highlighting the timeliness of the Featured Topic is a recent article in the New England Journal of Medicine (PMID:33406325) highlighting the role of ancestry and social factors such as racism in longstanding racial disparities in hypertension and how recent racial disparities incurred by the COVID-19 epidemic are thought to be at least partially attributable to disparities in cardiometabolic health and healthcare. Presentation of work from both human and animal studies are encouraged. Our featured speaker will be Dr. Austin Robinson of Auburn University, who will discuss the non-uniformity of the influences of dietary sodium on cardiovascular function and blood pressure regulation in different racial groups and across sexes, inclusive of data from the DASH-Sodium trials and original data. We will select presentations from submitted abstracts that deal with the themes of sex and racial differences in cardiovascular control irrespective of dietary sodium. We also welcome submissions that consider factors that are not traditionally considered to be “biological” – such as socio-economic disparities resulting from historic and contemporary inequity across racial groups.

Speakers

  • Introduction
    Nisha Charkoudian — Thermal & Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine
    1:30 PM - 1:35 PM

  • One Size Doesn't Fill All - Differential Effects of Dietary Sodium by Race and Sex
    Austin T Robinson — School of Kinesiology, Auburn University
    1:35 PM - 2:05 PM

  • Close
    Megan Wenner — Kinesiology and Applied Physiology, University of Delaware
    2:55 PM - 3:00 PM




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