APS Annual Meeting at Experimental Biology



Extracellular Vesicles as Targets for Cardiovascular Health

Symposium — Thursday, April 29, 2021 — 2:00 PM - 3:30 PM — Virtual Session, Room APS-6
The Physiological Society and APS — Chair: Susan Currie — Co-Chair:
Experimental Physiology

Cardiovascular disease remains the major cause of global mortality despite advances in disease treatment. Early detection of cardiovascular pathology is crucial for enhanced management and therapeutic treatment going forward. Extracellular vesicles (EVs) are emerging as potential candidates for novel biomarkers of cardiac injury, cardiotoxicity and also show potential as targets for therapeutic intervention. EVs play a role in intercellular communication across a number of cardiovascular cell types and, as such, may contribute to the progression of the pathophysiological process. This symposium will examine the current research strategies being considered for harnessing EVs in the diagnosis and treatment of various cardiovascular disorders. Particular focus will be given to the role EVs might serve as biomarkers of cardiac injury and how they may be used as therapeutic agents and drug delivery carriers going forward.

Speakers

  • Introduction
    Susan Currie — Institute of Pharmacy and Biomedical Sciences, University of Strathclyde Glasgow
    2:00 PM - 2:05 PM

  • The Impact on Extracellular Vesicles-mediated Communication in the Heart
    Henrique Girao — Institute of Biomedical Imaging and Life Sciences, University of Coimbra
    2:05 PM - 2:30 PM

  • Therapeutic Potential and Mechanistic Insight of Extracellular Vesicles in Vascular Disease
    Lorraine Work — Institute of Cardiovascular and Medical Sciences, University of Glasgow
    2:30 PM - 2:55 PM

  • Cardiovascular Exosomes in Cardiac Physiology and Pathophysiology
    Suresh K. Verma — Medicine - Cardiovascular Disease, University of Alabama at Birmingham
    2:55 PM - 3:20 PM

  • Conclusion
    Susan Currie — Institute of Pharmacy and Biomedical Sciences, University of Strathclyde Glasgow
    3:20 PM - 3:30 PM




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