APS Annual Meeting at Experimental Biology

Chronic and Acute Environmental Challenges and the Control of Autonomic and Respiratory Function

Symposium — Tuesday, April 27, 2021 — 10:00 AM - 11:30 AM — , Room APS-8
Pan-American Societies (SFiB) — Chair: Eduardo Colombari — Co-Chair: Daniel B Zoccal

The aim of this session will be to discuss the experimental and translational characteristics of chronic and acute environmental challenges affecting autonomic control and respiratory function. Speakers will discuss the supporting evidence for a crucial role played by the carotid body (CB) in the autonomic dysfunction, and the pros-and-cons of the CB elimination as a therapy to moderate autonomic overactivation. In addition, carotid chemoreflex is relevant for the dysregulation of the cardiovascular autonomic control during real-life physiological stressors in patients with pulmonary arterial hypertension. Consequently, the CB may be a potential target to treat cardiovascular autonomic dysfunction in this population. Postnatal chronic intermittent hypoxia (pCIH; 6% O2 every 9 min, 8 h/day), from P1 to P10 on the control of respiratory motor activity and sympathetic outflow of rats at adolescence and adulthood will also be explored.


  • Chronic and Acute Environmental Challenges and the Control of Autonomic and Respiratory
    Eduardo Colombari — Physiology and Phathology, School of Dentistry of Araraquara - UNESP

  • Interaction Among Reflexes for the Regulation of Exercise Hyperpnea in Healthy Humans and Patients with Cardiorespiratory Diseases
    Bruno Silva — Physiology, Federal University of Sao Paulo

  • Non-Respiratory Functions of the Carotid Body Chemoreceptor
    Rodrigo Iturriaga — Physiology Department Lab Neurology, Pontificia University Catolica de Chile

  • Impact of Post-Natal Intermittent Hypoxia on Central Cardiorespiratory Control in Adulthood
    Daniel B. Zoccal — Physiology and Pathology, Dentistry School of Araraquara - UNESP

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