Pathogenic Mechanisms of Electronic Cigarette or Vaping Associated Lung Injury (EVALI)
Nonfunded Featured Topic — Friday, April 30, 2021 — 10:00 AM - 11:30 AM — Virtual Session, Room APS-12
Respiration Section — Chair: Xinping Yue — Co-Chair: Denise Al Alam
There is an emerging appreciation of E-cigarettes and/or vaping as a novel cause of acute lung injury (EVALI). This Featured Topic, which is a refinement of a Scientific Symposium previously programmed for the 2020 EB meeting, seeks to incorporate state-of-the-art mechanistic studies of EVALI. Of note, this Featured Topic is designed for flexibilty to incorporate studies of COVID-19, which may be shaped by antecedent inhalational nicotine/vaping.
Speakers
- Introductions
Chairs, Dr. Xinping Xue and Dr. Denise Al Alam —
10:00 AM
- 10:02 AM
- Electronic-Cigarette Aerosol Exposures Cause Adverse Pulmonary Effects in Vitro and in Vivo
Alexandra Noel — Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine
10:02 AM
- 10:25 AM
- Moderated Discussion
Xinping Yue — Physiology, Louisiana State University Health Science Center
10:25 AM
- 10:30 AM
- Abstract 1 - Loss of Mitochondrial Adenine Nucleotide Translocase (ANT1) Regulates Cellular Senescence and Protects against Chronic Obstructive Pulmonary Disease
Corrine R. Kliment — Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh College of Medicine
10:30 AM
- 10:45 AM
- Abstract 2 - Cigarette or E-Cigarette Content Alters Autophagy and Permeability of Lung Endothelium
Mounica Bandela — Bioengineering, University of Illinois at Chicago
10:45 AM
- 11:00 AM
- Abstract 3 - Acetaldehyde in E-Cigarette Aerosol and Cigarette Smoke Exacerbate Pulmonary Microvascular Endothelial Dysfunction in ALDH2*2 Mice
Xuan Yu — Anesthesiology, Perioperative and Pain Medicine, Stanford University
11:00 AM
- 11:15 AM
- Abstract 4 - Toxicological Assessment of E-Cigarette or Vaping Product Use Associated Lung Injury (EVALI) Cartridges and Constituents
Thivanka Muthumalage — Environmental Medicine, University of Rochester Medical Center
11:15 AM
- 11:30 AM