APS Annual Meeting at Experimental Biology

Exercise, Aging and My-Old-Cardium: Beneficial Cardiovascular Adaptations to Exercise

Featured Topic — Wednesday, April 28, 2021 — 4:00 PM - 5:30 PM — Virtual Session, Room APS-8
Environmental and Exercise Physiology Section — Chair: Danielle Bruns — Co-Chair:

Endurance exercise is incredibly cardioprotective, evidenced in part by the significant predictive strength of cardiorespiratory fitness on cardiovascular disease mortality. Aging induces physiological and molecular changes in the heart, which ultimately result in diminished cardiac function and increased risk for development of heart disease. Aging also impacts the cardiac response to exercise, highlighting the critical need to understand how the aged heart responds to exercise and to identify strategies that improve exercise capacity in older populations. The goal of this featured topic is to explore the physiological and molecular basis for exercise as medicine in models of cardiac aging. Dr. Benjamin Levine, an expert in cardiac aging, will deliver the opening talk for this FT. He will first describe and define cardiac aging and then discuss exercise as medicine in clinical populations to reverse or prevent cardiac aging. This will set the stage for a featured topic session centered on the importance of exercise for the aging heart in translational models of cardiac aging. We anticipate a good selection of appropriate submitted abstracts to include in this FT, based on EB 2018-2019 abstracts featuring cardiac, aging, and exercise keywords. Programming for 2020 included several relevant abstracts aimed at understanding the impact of age on exercise-induced cardiovascular adaptations. To solicit a bigger selection of abstract submissions for 2021, strategies will include 1) targeted recruitment of relevant abstracts (this strategy was successful in 2020, but was unfortunately met with several last-minute cancellations by abstract submitters) and 2) casting of a wider net to also include keyword “cardiovascular”.


  • The “Sweet Spot” of Exercise Dose to Prevent or Reverse Cardiovascular Aging
    Ben Levine — Department of Internal Medicine, University of Texas Southwestern Medical Center

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