2019 About APS EB 2019 Information

Metabolism, Organ Crosstalk, Microbiome and Mechanisms

Symposium — Tuesday, April 9, 2019 — 1:30 PM - 3:00 PM — Convention Center, Room W311EF
Experimental Biology Symposium Series — Chair: Jun Sun — Co-Chair:

The human body harbors billions of microorganisms (including eukaryotes, archaea, bacteria and viruses) collectively referred to as the ‘microbiome’ that represents the largest exo-organ. Only recently have we begun to appreciate the role of microbiome in health and diseases. Environmental factors and change of life style including diet significantly shape human microbiome which in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Microbial metabolites may impact a number of host functions and are thus implicated in a variety of pathophysiological conditions, including intestinal disorders, e.g IBD and diarrhea, obesity, asthma, and even brain development. Approaches that can reshape the microbiome represent a reasonable strategy for potential therapeutic strategies. The goals of this symposium is to introduce the researchers and students with the recent progress in metabolism and microbiome on pathophysiology of human diseases. It will also provide opportunities for researchers to develop a collaborative relationship on this important topic. We will invite speakers including male and female investigators at difference career stages. We believe that physiologists and students working on digestive diseases, metabolic diseases, infectious diseases, and cancer benefited from this symposium. Microbiologists, immunologists, and physicians also had interests in this symposium. Opportunities for interdisciplinary interactions and international collaboration was significantly enhanced in this symposium. Suggested


  • Microbiome in Gut-Brain Axis
    Erika Claud — Dept. of Pediatrics, Univ. of Chicago

  • Association of Fecal Metabolites with Enteric Neuronal Survival/Impairment and Gastrointestinal Motility Disorders
    Shanthi Srinivasan — Dept. of Medicine, Digestive Diseases Lab, Emory Univ. Sch. of Med.

  • Pathogenesis, Immunity and the Role of Microbiome/Probiotics in Virus Infections in Humans and Animal Models
    Lijuan Yuan — Biomedical Sciences and Pathobiol., Virginia-Maryland Col. of Vet. Med.

  • Chair
    Jun Sun —

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