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Carotid Body Sensing: More than Just an O2 Sensor

Symposium — Sunday, April 7, 2019 — 3:30 PM - 5:00 PM — Convention Center, Room W308CD
Experimental Biology Symposium Series — Chair: Peter Matthew MacFarlane — Co-Chair: Ryan Bavis

There is a long-standing history that has been dedicated to teasing out the molecular mechanisms underlying oxygen sensing of the carotid body and the corresponding influence it has on respiratory control. More recent advances have begun to expand beyond the signal transduction mechanisms of oxygen sensing with emerging evidence that the sensory capabilities of the carotid body is highly diverse. The purpose of this session is to convene prominent figures in the field of oxygen sensing/signal transduction, and then bring to the forefront a complementary theme aimed at highlighting the emerging evidence that the sensory repertoire (e.g. glucose, insulin, immune/inflammatory, erythropoietin, leptin) of the carotid body may go far beyond oxygen. A greater understanding of carotid body sensing diversity will be a fundamental evolutionary step in our progress toward discovering the broader (patho)physiological roles it may play in health and disease.


  • Revisit Gasotransmitters in Carotid Body Oxygen Sensing
    Ying Jie Peng — Department of Medicine, University of Chicago

  • Carotid Body: The Link Between Oxygen and Metabolic Sensing
    Silvia Conde — Medical Sciences College, Nova Medical School, New University of Lisbon

  • The Effect of Inflammation on Peripheral and Central Reflexes that Control Breathing during Development
    Estelle Gauda — Pediatrics, University of Toronto, The Hospital for Sick Children

  • Chair
    Peter Matthew MacFarlane —

  • Co-Chair
    Ryan Bavis —

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