2019 About APS EB 2019 Information

Aquaporins: More than Water under the Bridge

Symposium — Sunday, April 7, 2019 — 8:30 AM - 10:00 AM — Convention Center, Room W311EF
Experimental Biology Symposium Series — Chair: Mykola Mamenko — Co-Chair: Daria Ilatovskaya
Cosponsored by AJP - Cell Physiology and AJP - Renal Physiology

It is becoming increasingly appreciated that aquaporin (AQP) function extends beyond facilitation of transmembrane water and solute transport. The accrued evidence suggests a critical role of water channels in inflammation and neuronal excitation, cell migration, proliferation, metabolism and intracellular lipid signaling. AQP-related disorders or aquaporinopathies include nephrogenic diabetes insipidus, polycystic kidney disease, congenital cataracts, neuromyelitis optica, infertility and psoriasis, to name a few. The scope of the proposed symposium is to summarize recent findings pertaining to aquaporin epithelial biology and its clinical applications. The session will feature novel discoveries revealing the role of classical water-permeable AQPs and glyceroaquaporins in keratinocytes, Sertoli cells and renal collecting duct principal cells, suggesting novel treatment strategies for psoriasis, male infertility and polyuria.


  • Aquaporin-3 in the Epidermis: More than Skin Deep
    Wendy Bollag — Department of Physiology, Augusta University

  • Aquaporin 2 and Water Balance: An Ever Evolving Story
    Hanne B. Moeller — Department of Biomedicine, Aarhus University

  • The Role of Aquaporins and Glycerol Metabolism in Male Fertility
    Pedro Fontes Oliveira — Institute for Innovation and Health Research, University of Porto

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