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The Role of Skeletal Muscle Damage in Adaptive Remodeling

Symposium — Sunday, April 7, 2019 — 1:30 PM - 3:00 PM — Convention Center, Room W314
Environmental and Exercise Physiology Section — Chair: John Joseph McCarthy — Co-Chair: Kevin A. Murach
Cosponsored by J. Appl. Physiol.

Skeletal muscle remodeling is a multi-faceted process that involves sensing of tension at the muscle fiber membrane that ultimately results in an adaptive signaling response. Muscle damage often occurs with loading, and it is thought that damage is an important contributor to the remodeling process, but the direct evidence for this is unclear. This symposium brings together experts in the field to discuss how muscle fiber damage contributes to skeletal muscle fiber remodeling.


  • Hypertophy, Satellite Cells, and Skeletal Muscle Damage
    Kevin A. Murach — Rehabilitation Sciences, University of Kentucky

  • The Development of Skeletal Muscle Hypertrophy through Resistance Training: The Role of Muscle Damage and Muscle Protein Synthesis
    Felipe Damas — Physical Education and Sport, University of São Paulo

  • The Role of Pericytes in the Repair of Skeletal Muscle Damage
    Marni Boppart — Department of Kinesiology and Community Health, University of Illinois

  • Effects of high intensity intermittent running training protocols with concentric- vs. eccentric-contraction bias on human skeletal muscle satellite cell dynamics and fiber adaptation
    Kathryn Helen Myburgh — Physiological Sciences, Stellenbosch University

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