2019 About APS EB 2019 Information

Cardiovascular Metabolism in Diabetes

Featured Topic — Tuesday, April 9, 2019 — 8:30 AM - 10:00 AM — Convention Center, Room W311C
Cardiovascular Section — Chair: Bradford G Hill — Co-Chair: Romain Harmancey
Cosponsored by: AJP - Heart and Circulatory Physiology

Cardiovascular disease is the leading cause of death in diabetic patients.  Metabolic plasticity and reprogramming of cellular metabolic pathways has emerged as a key control mechanism for the maintenance of cardiovascular homeostasis, with established roles in preservation of energy generation by cardiac myocytes, regulation of angiogenesis, and resolution of the inflammatory response.  Consequently, altered cellular metabolism is being increasingly recognized as a major determinant of cardiac failure following diabetes-associated cardiovascular events such as myocardial infarction and chronic hypertension.  This featured topic session will provide an update on the recent advances in our understanding of the molecular mechanisms controlling the metabolic adaptation and reprogramming of cells from the cardiovascular system in response to environmental stress, and of their alteration by the dysregulated hormonal and metabolic milieu of diabetes.


  • Molecular Basis of Postischemic Maladaptation in the Insulin Resistant Heart
    Romain Harmancey — Physiology and Biophysics, University of Mississippi Medical Center

  • Abstract
    Jessica L. Faulkner — Vascular Biology Center, Medical College of Georgia at Augusta University

  • Abstract
    Alice E. Zemljic-Harpf — Anesthesiology, Veterans Administration San Diego Healthcare System, and Univ. of California, San Diego

  • Abstract
    John J. Reho — University of Iowa

  • Abstract
    Norita Gildea — Trinity College Dublin

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