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The Clinical and Metabolic Benefits of Exercise for People with Type 1 Diabetes

Symposium — Tuesday, April 9, 2019 — 3:30 PM - 5:00 PM — Convention Center, Room W311B
The Physiological Society-UK (PHYSOC) — Chair: Anton JM Wagenmakers — Co-Chair: Parth Narendran

People with type 1 diabetes (T1D) are recommended to perform regular physical activity as it has benefits on metabolic and cardiovascular health and increases lifespan. However, the majority of T1D patients do not meet physical activity guidelines and are overweight or obese. Fear of hypoglycemia during and post exercise is a major barrier to exercise for T1D patients and their health care providers. This symposium brings together experts in clinical and basic T1D research and skeletal muscle physiology to present an overview of the latest knowledge on the multiple benefits of exercise. Cynthia Monaco presents research showing that alterations in mitochondrial ultrastructure and bioenergetics are already present in skeletal muscle of young adults with T1D and may be leading to premature muscle ageing. Sam Scott introduces a novel home-based high-intensity interval-training program, which reduces the high barriers to exercise for the T1D population and improves glucose homeostasis, aerobic capacity and (cardio)vascular health. Parth Narendran presents research showing that an increase in physical activity levels to 150-240 min of moderate exercise per week may preserve β cell function in recent onset T1D. Rob Andrews presents unpublished data on what happens to glucose control whilst training for and completing a half marathon and how patients manage their glucose during this time.


  • Evidence of Early Alterations to Muscle 'Health' in People with Type 1 Diabetes
    Cynthia Monaco — Department of Pathology & Molecular Medicine, McMaster University

  • A Multi-Disciplinary Evaluation of Home-Based High-Intensity Interval Training in People with Type 1 Diabetes
    Sam Scott — Research Institute for Sport and Exercise Sciences, Liverpool John Moores University

  • Physical Exercise for Preservation of Beta Cell Function in Patients with Type 1 Diabetes
    Parth Narendran — Institute of Immunology and Immunotherapy, University of Birmingham

  • Glucose Management during Training and Half Marathon Running. Results of the EXTOD101 Study
    Rob Andrews — Medical Research, University of Exeter Medical School

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