2019 About APS EB 2019 Information

Hormonal Influences on Tissue Remodeling

Symposium — Sunday, April 7, 2019 — 3:30 PM - 5:00 PM — Convention Center, Room W311A
Endocrinology and Metabolism Section — Chair: Sarah H. Lindsey — Co-Chair: Eman Y. Gohar

Pregnancy induces adaptive remodeling of multiple physiologic systems, including alterations in structure and function of cardiovascular, musculoskeletal, and reproductive tissues. Menopause, on the other hand, is associated with maladaptive remodeling and an increase in diseases such as hypertension, diastolic dysfunction, urinary incontinence, pelvic prolapse, and osteoporosis. Hence, there is a pressing need to better understand the mechanisms by which estrogen and other hormones influence tissue homeostasis and remodeling during aging, pregnancy, disease, and injury. This symposium will highlight research across an array of fields with the common thread of understanding how female tissues grow and remodel in response to sex hormone changes across the life cycle. This symposium will serve as a vital first step towards elucidating potential sex differences in tissue remodeling and advancing women’s health.


  • Impact of Estrogen on Left Ventricular Remodeling and Function
    Jason D. Gardner — Physiology, LSUHSC-New Orleans

  • Dysregulation of Uteroplacental and Vascular Remodeling and the Matrix Metalloproteinases, Gelatinases, Collagenases, and Matrilysin During Hypertension in Pregnancy
    Raouf A. Khalil — Division of Vascular Surgery, Harvard University

  • Membrane-Initiated Estrogenic Signaling and Vascular Remodeling
    Benard O Ogola — Pharmacology, Tulane University

  • Interactive Effects of Exercise and estrogen on the Skeletal System
    Wendy M. Kohrt — Medicine/Geriatrics, University of Colorado Denver

    Sarah H. Lindsey —

    Eman Y. Gohar —

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