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Nutrition as a Biological Variable: Considerations for the Future of Physiology Research

Symposium — Sunday, April 7, 2019 — 3:30 PM - 5:00 PM — Convention Center, Room W311C
Nutrition Physiology Interest Group — Chair: Tracy G. Anthony — Co-Chair: Jamie I. Baum
Cosponsored by AJP - Gastrointestinal and Liver Physiology and J. Appl. Physiol.

The NIH is currently seeking input from the scientific community to develop a Nutrition Roadmap for federal funding.  Part of this initiative is aimed toward increasing scientific rigor and reproducibility by defining and establishing common diet standards and controls.  Use of chow as a control has always received criticism among traditional nutrition scientists, leading to the establishment of defined standard diets decades ago (e.g., AIN76 and AIN93 rodent diets) and yet, chow remains a common diet control in many scientific fields who utilize rodent models.  A proliferation of obesity-related research has led to the common use of the high fat diet to provoke diet-induced obesity; however, the composition of the high fat diet can vary widely, not only in amount but in macronutrient composition.  Challenges in dietary control become further amplified in clinical studies, where individual variation is compounded by personal choice and behavior.  How to consider, control and correct for these variables is the subject of this forward-thinking symposium.  Among the various fields of study in physiology, there is renewed interest in establishing nutrient standards for all species. The time is right to challenge the membership to consider these issues more thoughtfully.  The aim of this symposium is to provide a primer and roadmap for how to better design a nutrition experiment no matter what the research model.


  • Considering Nutrition as a Biological Variable and the Strategic Plan for NIH Nutrition Research
    Christopher J Lynch — Office of Nutrition Research, National Institutes of Health

  • Food Intake in Clinical Research Studies: How Much Dietary Control and for How Long?
    Elizabeth J Parks — Nutrition & Exercise Physiology, University of Missouri

  • Nutrition and Circadian Rhythms in Obesity
    Joseph T Bass — Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University

  • Chair
    Tracy Anthony —

  • Co-Chair
    Jamie Baum —

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