2019 About APS EB 2019 Information

Muscle-Derived Extracellular Vesicles in the Regulation of Metabolic Health and Disease

Symposium — Tuesday, April 9, 2019 — 8:30 AM - 10:00 AM — Convention Center, Room W308AB
Muscle Biology Group — Chair: Daniel Lark — Co-Chair:

Abstract: In recent years, a growing body of literature has implicated extracellular vesicles like exosomes as an important means of inter-organ communication.  Extracellular vesicles are released by skeletal muscle in large quantities in response to exercise, suggesting their involvement in the systemic benefits of physical activity.  Similarly, metabolic diseases like obesity are also linked to elevated levels of extracellular vesicles, emphasizing a need for better understanding why/how EVs are released and what they contain.  This symposium will feature speakers at the leading edge of extracellular vesicle biology as it relates to exercise and/or metabolic disease with a focus on skeletal and cardiac muscle.


  • Fibroblast-Derived Exosomes Regulate Extracellular Matrix Remodeling
    Charlotte Peterson — University of Kentucky

  • Exercise Promotes Secretion of Exosomes from Human Skeletal Muscle
    Martin Whitham — Diabetes and Metabolism, Garvan Institute of Medical Research

  • Extracellular Vesicles as Signalling Mediators in Diabetes Mellitus
    Nicole Noren Hooten — Health Disparities Res. Sect., NIA, NIH

  • Chair
    Daniel Lark —

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